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# For hypertension with a diuretic effect # **Tags:** * Cardiovascular Diseases Of The Army * Dr. blood pressure * Effective pills for high blood pressure :::warning Diuretiko (Diuretika) ay nagpapataas ng pag-ihi ng katawan, na nagreresulta sa pagbaba ng presyon ng dugo. Simpleng paliwanag: Ang tuloy-tuloy na pag-ihi ng katawan ay nagdudulot ng pagbaba ng dami ng plasma sa dugo at sa gayon ay mas kaunting likido sa mga ugat — bumababa ang presyon sa mga pader ng ugat. ::: [![](https://cardio-balance-ph.store-best.net/img/go2.png)](https://cardio-balance-ph.store-best.net) <div style="height:500px;"></div> ## Cardiovascular Diseases Of The Army ## <div class="alert alert-info" role="alert"> Ginagamit ito bilang biologically active na pampadagdag sa pagkain - dagdag na pinagmumulan ng mga bitamina - B2, B6, C, mga organikong asido - mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6. </div> For high blood pressure with urinary effect: diuretics driving as a major method of therapy High blood pressure, known medically as hypertension, is one of the most common chronic diseases in modern societies and is considered an important risk factor for cardiovascular diseases such as heart attack and stroke. An effective reduction in blood pressure reduces the risk of these complications significantly. An important group of drugs for the treatment of hypertension are diuretics, also as a diuretic agent. Their effect is based on the influence of renal function: promote the excretion of water and salts (especially sodium) in the urine, thereby reducing the volume of blood decreases in the body. Mechanism of action Diuretics interfere at various Points in the renal tubular: Thiazides (eg, hydrochlorothiazide): to act in the distal tubule and are often the first choice in the treatment of mild-to-moderate hypertension. Loop diuretics (e.g., furosemide): attack in the loop of Henle, and have a strong, rapid onset of diuretic action. They are primarily used for severe hypertension or concomitant heart failure. Potassium-saving diuretics (e.g., spironolactone): work at the end of the tubule system, and prevent too much potassium loss may occur in the use of other diuretics. Due to the reduction of the blood volume, the blood pressure (arterial pressure) decreases as the heartbeat must work against a lower resistance. In the long term, the reduction of sodium in the tissue also contributes to the Relaxation of the blood walls of the vessel, which reduces the peripheral vascular resistance. Clinical effectiveness and use Numerous clinical studies have proven the effectiveness of diuretics in the treatment of hypertension. They are particularly effective in older patients and in patients with volume overload. They are often prescribed in combination with other antihypertensives (e.g., ACE inhibitors, beta‑blockers), in order to optimize the reduction in blood pressure and to minimize side effects. Side effects and precautions Despite the effectiveness of diuretics can lead to side effects, including: Electrolyte disturbances (for example, potassium deficiency in a Thiazide and loop diuretics), Dehydration, elevated uric acid levels (which can cause gout), Blood sugar and lipid changes (in the case of high doses of a Thiazide). Frequent monitoring of electrolyte levels (particularly potassium and sodium) and renal function during therapy is essential. Conclusion Diuretics due to its proven mechanism of action, their effectiveness and their cost advantage is a cornerstone of therapy in the treatment of hypertension. Individual dosage and careful Monitoring to enable a safe and successful lowering blood pressure, reducing the risk of cardiovascular complications sustainably reduced. > Ginagamit ito bilang biologically active na pampadagdag sa pagkain - dagdag na pinagmumulan ng mga bitamina - B2, B6, C, mga organikong asido - mansanas, succinic, glutamine. Mga sangkap: malic acid, succinic acid, glutamic acid, badan extract, ascorbic acid, bitamina B2, B6. ![](https://cardio-balance-ph.store-best.net/img/2.jpg) <a href="https://hedge.grin.hu/s/m8LXgWL2bk">https://hedge.grin.hu/s/m8LXgWL2bk</a> Minsan lang na biglaang pagtaas ng presyon o bahagyang mataas na resulta ay hindi palaging nangangailangan ng agarang pag-inom ng tableta. 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The reduction in blood pressure by drug therapy can reduce the risk of these complications significantly. Goals of therapy The goal of blood pressure therapy is to keep the blood pressure in the long term under 140/90 mmHg (millimeters of Mercury), in patients with Diabetes or kidney disease, even under 130/80 mmHg. This is usually achieved by a combination of lifestyle changes (healthy diet, exercise, weight reduction, avoiding Smoking and excessive alcohol consumption) and medications. Important groups of Drugs for high blood pressure There are different classes of blood pressure core, the work in different ways. The most important are: ACE inhibitors (Angiotensin‑converting enzyme inhibitors): Mechanism of action: Inhibit the enzyme ACE, the formation of the Pressor substance Angiotensin II is responsible. As a result, the vasoconstriction is prevented, and the blood pressure is lowered. Examples: Ramipril, Enalapril, Lisinopril. Side effects: cough, cardiovascular reactions (e.g. dizziness), increased levels of potassium. AT1‑receptor blockers (Sartans): Mechanism of action: Blocking the effect of Angiotensin II to its receptors, which also leads to a relaxation of the blood vessels. Examples: Losartan, Valsartan, Candesartan. Side effects: Similar to ACE inhibitors, but the cough occurs less frequently. Calcium antagonists: Mechanism of action: Prevent the vessels of the influx of calcium ions into the smooth muscles of the blood, which leads to vasodilatation and, consequently, to a reduction in blood pressure. Examples: Amlodipine, Nifedipine, Diltiazem. Side effects: swelling of the legs (Edema), redness of the face, tachycardia. Diuretics (diuretics): Mechanism of action: Result in increased excretion of water and salt through the kidneys, reducing the blood volume and thus blood pressure decreases. Examples: hydrochlorothiazide, indapamide, furosemide (in severe cases). Side effects: loss of Electrolyte (e.g., potassium), thirst, increased blood sugar and uric acid levels. Beta-blockers: Mechanism of action: Dampen the effects of the stress hormone adrenaline on the heart. The heart beats slower and weaker, causing the blood pressure drops. Examples: Metoprolol, Bisoprolol, Carvedilol. Side effects: fatigue, coldness of the limbs, impaired blood sugar control. Combination therapy and individual adjustment Often the gift of a single specimen is not sufficient to reach the goal. In such cases, two or more drugs from different drug groups are combined. This increases the effectiveness and minimize the side effects, since lower doses can be used. The therapy must always be individually adjusted. The following factors play a role: The age of the patient, The presence of concomitant diseases (Diabetes, kidney disease, congestive heart failure), possible side effects and interactions with other drugs, personal preferences of the patient. Conclusion The pharmacotherapy of hypertension is based on a broad Foundation of effective groups of Drugs. The proper selection and combination of these substances, based on individual patient characteristics, allows for the effective control of blood pressure and contributes significantly to the prevention of life-threatening complications. Close coordination between the physician and the Patient, is of crucial importance.